Pyruvate and dihydroxyacetone (DHAP) are marketed as nutritional supplements by health food stores and multilevel marketing distributors. Claims for pyruvate and dihydroxyacetone range from increasing endurance capacity, augmenting weight and fat loss, decreasing appetite, increasing metabolism, acting as an antioxidant, and lowering plasma lipids. Although several laboratory and clinical studies have investigated these claims, no studies to date have demonstrated the effectiveness of DHAP in improving athletic performance.